• Bottle of 300 water soluble 400 IU Vitamin E soft gels • Works as antioxidant by fighting free radicals • Protects body's cells from compounds such as lead and mercury; contains 1333% RDA of Vitamin E per soft gel serving • Water-soluble vitamin E is intended for those who have difficulty absorbing fat • Founded in 1971, Northridge, California-based Pharmavite manufactures Nature Made vitamins and Nature's Resource herbal products and was instrumental in developing Good Manufacturing Practices (GMPs) for supplements
Customer Rating: Summary: Garbage Vitamin E Comment: There are several problems with this vitamin E:
1) Its synthetic. Synthetic vitamin E is problematic because the vitamin E molecule has 3 chiral centers. So only 1/2^3, or 1/8 of the material is identical to naturally occuring vitamin E. The other 7 forms have never been studied and may be toxic. Studies performed with synthetic E have shown toxic and damaging effects.
2) Its only alpha tocopherol. There are 3 other tocopherols and 4 other tocotrienols that are in the vitamin E family. The gamma tocopherol form seems to be especaillay important. Taking large doses of the alpha form depletes gamma tocopherol levels.
3) Its esterified (the succinate form I think), which means that its not really an antioxidant. The esterification process removes the reducing capacity of vitamin E.
the bottom line is that this product is junk and probably damaging to your health. The people that say that synthetic E is the same as natural vitamin E dont know what they are talking about. Stereochemistry and chirality are extremely important in biochemistry. For example, amino acids are always in the "L" form, the "D" stereoisomers of some amino acids can be deadly. This product is mostly (about 85%) a collection of random stereoisomers of vitamin E that do not occur naturally. It ought to be illegal to sell this stuff, really. Customer Rating: Summary: vitamins Comment: These vitamins came quickly. And I use this product all the time, I believe that these vitamins are very best! Customer Rating: Summary: Product bottle shows that it actually contains "dl-Alpha Tocopherol Acetate" as the main ingredient. Comment: The description of the ingredients lists "d-Alpha Tocopherol Acetate" as the main ingredient. However, the product bottle indicates that the actual main ingredient is "dl-Alpha Tocopherol Acetate", an articial and very different version of the advertised ingredient. The Amazon.com listing is very misleading. Customer Rating: Summary: Vitamin E Can be Toxic in High Dosages Comment: Vitamin E is a fat-soluble vitamin, meaning it is an oil-based vitamin. All the oil based vitamins are stored in the liver or in body fat cells. When too much of a fat soluble vitamin is ingested, the excess is stored in fat. If too much is ingested over a period of time, the excess vitamin can become toxic. Thus, taking too much of a fat-soluble vitamin can be dangerous to your health.
This formualtion of Vitamin E, at 400 IU's is perhaps too great a dose to take in my opinion. I much prefer the 200 IU dose (or less). The recommended daily allowance (in adults) for Vitamin E set by the FDA is only 15 mg a day.
Vitamin E is a fat-soluble vitamin that exists in eight different forms. Each form has its own biological activity, which is the measure of potency or functional use in the body [1]. Alpha-tocopherol (á-tocopherol) is the name of the most active form of vitamin E in humans.
Vitamin E is a powerful antioxidant and it attaches itself to free radicals (by-products of metabolism that can harm the body), and neutralize them. Vitamin E can have beneficial effects on the skin, the heart, and the immune system. Vegetable oils, nuts, green leafy vegetables, and fortified cereals are common food sources of vitamin E in the United States.
Long-term supplementation (over a year) with Vitamin E has not been adequately studied, thus it is best to take a 200 IU dose or LESS. I would stay clear of the higher dosages.
Jim "Konedog" Koenig Customer Rating: Summary: Great Product, Lousy Service Comment: The product is great, but I'm having to continue to buy it at K-Mart. I ordered it here under a special offer in March 2004 with some other items to qualify for free shipping; delayed shipment of this item is holding another in-stock item hostage (they won't ship it separately unless I cancel this item) until this item becomes available, possibly as late as March 2005! I'm just letting the order ride to see how long it takes them! Amazon, you're losing my respect!